2. Academic Validation
  3. A Julolidine Aldehyde Dansyl Hydrazine Schiff Base as Fluorescence Chemosensor for Zn2+ ions Recognition and its Application

A Julolidine Aldehyde Dansyl Hydrazine Schiff Base as Fluorescence Chemosensor for Zn2+ ions Recognition and its Application

  • J Fluoresc. 2025 Jun;35(6):4547-4557. doi: 10.1007/s10895-024-03842-2.
A Asrar Ahamed 1,  Sulaiman Ali Alharbi 2,  Geetha Venkatesan 3
Affiliations

Affiliations

  • 1 PG and Research Department of Chemistry, Jamal Mohamed College (Autonomous), Affiliated to Bharathidasan University, Tiruchirappalli-620020, Tamil Nadu, India.
  • 2 Department of Botany and Microbiology, College of Science, King Saud University, PO Box -2455, Riyadh - 11451, Saudi Arabia.
  • 3 Department of Biomaterials, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 600 077, India. [email protected].
PMID: 39042356 DOI: 10.1007/s10895-024-03842-2
Abstract

The Schiff base fluorescent probe (Dz-Jul), containing julolidine aldehyde and dansyl hydrazine, was derived using a simple condensation. This chemosensor showed high selectivity towards Zn2+ and quick response (170 s) in DMSO/H2O solutions (8/2, v/v, pH 7.2 buffer). A fluorometric titration determined that Dz-Jul-Zn2+ has a binding ratio of 1:1, and the association constant (Ka) is 1.03 × 105 M-1. The Dz-Jul detection limit of Zn2+ ions was 15 nM, much lower than the WHO standard (76.0 nM). DFT, ESI mass, and FTIR spectral demonstrated a plausible complexation mode between Dz-Jul and Zn2+ ions. In actual water samples, Zn2+ has been detected with good detection performance using Dz-Jul. Additionally, Dz-Jul-coated test strips allowed for rapid and qualitative monitoring of Zn2+ ions in a visible manner.

Keywords

Chemosensors; Dansyl hydrazine; Fluorescence; Julolidine; Schiff Base; Zinc Ions.

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