1. Academic Validation
  2. Blue light irradiation induces skin barrier damage through EGFR/ERK/c-Jun signaling pathway

Blue light irradiation induces skin barrier damage through EGFR/ERK/c-Jun signaling pathway

  • J Invest Dermatol. 2026 Feb 23:S0022-202X(26)00102-8. doi: 10.1016/j.jid.2026.02.007.
Yang Xu 1 Lei Lu 1 Peiyi Liu 1 Yiyu Wang 2 Jing Ning 3 Rui Zhang 4 Ge Ge 5 Qi Xi 1 Jiahua Wen 1 Xiance Chen 1 Yiyang Lei 1 Xinyuan Zhang 6 Yulong Tang 7 Weilin Pu 1 Yimei Tan 4 Wei Liu 2 Jiucun Wang 8 Yanyun Ma 9
Affiliations

Affiliations

  • 1 College of Biomedical Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai, People's Republic of China; School of Life Sciences, State Key Laboratory of Genetics and Development of Complex Phenotypes, Fudan University, Shanghai, People's Republic of China.
  • 2 Department of Dermatology, Air Force Medical Center, PLA (People's Liberation Army), Beijing, People's Republic of China.
  • 3 Department of Medical Cosmetic, Burn and Plastic Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
  • 4 Department of Skin and Cosmetic Research, Shanghai Skin Disease Hospital, Shanghai, People's Republic of China.
  • 5 Department of Dermatology, The Seventh Medical Center of PLA General Hospital, Beijing, People's Republic of China.
  • 6 Shanghai Skinshield Clinical Testing and Technological Research, Shanghai, People's Republic of China.
  • 7 College of Biomedical Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai, People's Republic of China.
  • 8 School of Life Sciences, State Key Laboratory of Genetics and Development of Complex Phenotypes, Fudan University, Shanghai, People's Republic of China; Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058), Chinese Academy of Medical Sciences, Shanghai, People's Republic of China; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China. Electronic address: [email protected].
  • 9 College of Biomedical Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai, People's Republic of China; Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058), Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. Electronic address: [email protected].
Keywords

Blue light exposure; EGFR; Epidermal thickening; Keratinocytes; MAPK.

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