1. Academic Validation
  2. The discovery, fermentation, isolation, and structure of antibiotic A33853 and its tetraacetyl derivative

The discovery, fermentation, isolation, and structure of antibiotic A33853 and its tetraacetyl derivative

  • J Antibiot (Tokyo). 1984 May;37(5):441-5. doi: 10.7164/antibiotics.37.441.
K H Michel L D Boeck M M Hoehn N D Jones M O Chaney
Abstract

The structure of Antibiotic A33853, isolated from the culture broth of Streptomyces sp., NRRL 12068, is reported. The structure was deduced from an X-ray crystallographic study of its tetraacetyl derivative. Tetraacetyl A33853 is unique because it contains an anhydride moiety, an unexpected product from the reaction of A33853 with acetic anhydride and pyridine.

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