2. Academic Validation
  3. Serotonergic receptor antagonist from Nandina domestica Thunberg

Serotonergic receptor antagonist from Nandina domestica Thunberg

  • J Pharm Sci. 1984 Apr;73(4):568-70. doi: 10.1002/jps.2600730435.
N Shoji,  A Umeyama,  T Takemoto,  Y Ohizumi
PMID: 6726648 DOI: 10.1002/jps.2600730435
Abstract

A crude methanolic extract of the fruit of Nandina domestica Thunberg strongly inhibits serotonin-induced contractions of the rabbit aorta. The extract of the fruit has been fractionated to afford nantenine (O- methyldomesticine ) as the active agent.

Figures
Products