2. Academic Validation
  3. New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum

New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum

  • J Nat Prod. 1995 Nov;58(11):1655-61. doi: 10.1021/np50125a002.
C H Chen 1,  S W Yang,  Y C Shen
Affiliations

Affiliation

  • 1 School of Pharmacy, National Taiwan University, Taipei, Republic of China.
PMID: 8594142 DOI: 10.1021/np50125a002
Abstract

Three new Steroids, zhankuic acids A [1], B [2], and C [3], were isolated from the fruiting bodies of Antrodia cinnamomea by bioassay-guided fractionation. The structures of these compounds were elucidated by chemical reactions and detailed analysis of their 1H- and 13C-nmr spectra. Biological studies revealed that 1 exhibited cytotoxic activity against P-388 murine leukemia cells and 2 showed weak anticholinergic and antiserotonergic activities.

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