2. Others
  3. Drug Derivative
  4. Mesulergine

Mesulergine is an active compound.

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Mesulergine

Mesulergine Chemical Structure

CAS No. : 64795-35-3

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Other Forms of Mesulergine:

Mesulergine Related Antibodies

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Description

Mesulergine is an active compound.

Cellular Effect
Cell Line Type Value Description References
CHO-K1 IC50
120 nM
Compound: Mesulergine
Antagonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as inhibition of serotonon-induced increase in cAMP levels by HTRF assay relative to untreated control
Antagonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as inhibition of serotonon-induced increase in cAMP levels by HTRF assay relative to untreated control
[PMID: 19326916]
HEK293 IC50
0.29 μM
Compound: Mesulergine
Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTRF assay
Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTRF assay
[PMID: 25073094]
Masse moléculaire

362.49

Formule

C18H26N4O2S
CAS No.
SMILES

O=S(N[C@@H](C[C@@]12[H])CN(C)[C@]1([H])CC3=CN(C)C4=C3C2=CC=C4)(N(C)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Mesulergine Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mesulergine64795-35-3Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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