2. Neuronal Signaling
  3. Amyloid-β
  4. Mivelsiran

Mivelsiran is a siRNA targeted to amyloid-beta precursor protein (APP). It is used for the study of Alzheimer's disease.

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RNA, ((5',6'-dideoxy-6'-phosphono-β-D-ribo-hex-5-enofurano)Um-sp-(2'-deoxy-2'-fluoro)U-sp-Am-Gm-Gm-Um-(3'→3')-[1-de-β-D-ribofuranosyl-1-[(2S)-2,3-dihydroxypropyl]]m5U-(2'→5')-Gm-Gm-Am-Um-dT-Um-(2'-deoxy-2'-fluoro)U-Cm-dG-Um-Am-Gm-Cm-Cm-sp-Gm-sp-Um), complex with RNA (Gm-sp-Gm-sp-Cm-Um-Am-(2'-O-hexadecyl)C-Gm-Am-dA-Am-dA-Um-Cm-Cm-Am-Am-Cm-Cm-Um-sp-Am-sp-Am) (1:1)

Mivelsiran Chemische Struktur

CAS. Nr. : 2572991-83-2

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Beschreibung

Mivelsiran is a siRNA targeted to amyloid-beta precursor protein (APP). It is used for the study of Alzheimer's disease.

Klinische Studie
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

[Mivelsiran]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Reinheit & Dokumentation
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Mivelsiran Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mivelsiran2572991-83-2ALN-APPAmyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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