Montelukast acyl-b-D-glucuronide  (Synonyms: Montelukast AG)

Montelukast acyl-b-D-glucuronide (Montelukast AG) is a acyl glucuronide metabolite of Montelukast (HY-13315A)^[1].

Montelukast acyl-b-D-glucuronide exhibits high stability in 0.1 M KPB (pH 7.4) with a half-life of 37.5 h, exhibits moderate stability in 4% HSA solution (pH 7.4) with a half-life of 21.8 h, and exhibits low stability in human fresh plasma (pH 7.4) with a half-life of 1.7 h^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

762.31

C₄₁H₄₄ClNO₉S

188717-17-1

O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O)OC(CC2(CS[C@H](CCC3=C(C=CC=C3)C(C)(O)C)C4=CC=CC(/C=C/C5=NC6=C(C=C5)C=CC(Cl)=C6)=C4)CC2)=O)C(O)=O)O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Sawamura R, et al. Predictability of idiosyncratic drug toxicity risk for carboxylic acid-containing drugs based on the chemical stability of acyl glucuronide. Drug Metab Dispos. 2010;38(10):1857-1864.