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Moscatin inhibits AA-induced platelet aggregation in a concentration-dependent manner with IC50 values 37.2 μM .

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Moscatin

Moscatin Chemische Struktur

CAS. Nr. : 108335-06-4

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Beschreibung

Moscatin inhibits AA-induced platelet aggregation in a concentration-dependent manner with IC50 values 37.2 μM [1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 13
Cytotoxicity against human A549 cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human A549 cells assessed as decrease in cell viability after 6 days by MTT assay
[PMID: 27310249]
HL-60 IC50
19.15 μM
Compound: Moscatin
Cytotoxicity against human HL60 cells after 48 to 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 to 72 hrs by MTT assay
[PMID: 30684866]
HeLa IC50
> 10 μM
Compound: 13
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 6 days by MTT assay
[PMID: 27310249]
MCF7 IC50
> 10 μM
Compound: 13
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 6 days by MTT assay
[PMID: 27310249]
Platelet IC50
37.2 μM
Compound: 2
Antiplatelet activity against washed rabbit platelet assessed as inhibition of arachidonic acid-induced platelet aggregation preincubated for 3 mins by turbidimetric method
Antiplatelet activity against washed rabbit platelet assessed as inhibition of arachidonic acid-induced platelet aggregation preincubated for 3 mins by turbidimetric method
[PMID: 7798962]
Molekulargewicht

240.25

Formel

C15H12O3

CAS. Nr.
SMILES

OC1=CC(OC)=C2C3=C(O)C=CC=C3C=CC2=C1

Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation
Verweise
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  • Molaritätsrechner

  • Verdünnungsrechner

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
Moscatin
Art. -Nr.:
HY-N5035
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