MTSEA hydrobromide

Name: MTSEA hydrobromide
Brand: MedChemExpress
SKU: HY-120128
Rating: 4.5 (0 reviews)

Cat. No.: HY-120128 Pureza: 97.90%: Ficha de datos
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MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine.

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MTSEA hydrobromide Estructura química

No. CAS : 16599-33-0

Tamaño	Stock	Cantidad
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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Descripciòn

MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	154 3 Compound: ACS 42	Antiproliferative activity against human A549 cells after 3 days Antiproliferative activity against human A549 cells after 3 days	[PMID: 18294844]
A549	IC₅₀	154 3 Compound: ACS 42	Antiproliferative activity against human A549 cells after 3 days Antiproliferative activity against human A549 cells after 3 days	[PMID: 18294844]
A549	IC₅₀	154 3 Compound: ACS 42	Antiproliferative activity against human A549 cells after 3 days Antiproliferative activity against human A549 cells after 3 days	[PMID: 18294844]
HeLa	IC₅₀	198 3 Compound: ACS 42	Inhibition of human HDAC in HeLa cells Inhibition of human HDAC in HeLa cells	[PMID: 18294844]
HeLa	IC₅₀	198 3 Compound: ACS 42	Inhibition of human HDAC in HeLa cells Inhibition of human HDAC in HeLa cells	[PMID: 18294844]

In Vitro

Cys modification by MTSEA reduces susceptibility to Cd activation of receptors with A8C or L10C substitutions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

236.15

Fòrmula

C₃H₁₀BrNO₂S₂

No. CAS

16599-33-0

Appearance

Solid

Color

White to off-white

SMILES

CS(=O)(SCCN)=O.Br

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : 50 mg/mL (211.73 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.2346 mL	21.1730 mL	42.3460 mL
5 mM	0.8469 mL	4.2346 mL	8.4692 mL
10 mM	0.4235 mL	2.1173 mL	4.2346 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 97.90%

Select Batch:

Ficha de datos (270 KB) SDS (393 KB)

COA (248 KB) HNMR (238 KB) RP-HPLC (279 KB) MS (69 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Wilding TJ, et al. Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing. J Gen Physiol. 2019 Apr 1;151(4):435-451. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.2346 mL	21.1730 mL	42.3460 mL	105.8649 mL
	5 mM	0.8469 mL	4.2346 mL	8.4692 mL	21.1730 mL
	10 mM	0.4235 mL	2.1173 mL	4.2346 mL	10.5865 mL
	15 mM	0.2823 mL	1.4115 mL	2.8231 mL	7.0577 mL
	20 mM	0.2117 mL	1.0586 mL	2.1173 mL	5.2932 mL
	25 mM	0.1694 mL	0.8469 mL	1.6938 mL	4.2346 mL
	30 mM	0.1412 mL	0.7058 mL	1.4115 mL	3.5288 mL
	40 mM	0.1059 mL	0.5293 mL	1.0586 mL	2.6466 mL
	50 mM	0.0847 mL	0.4235 mL	0.8469 mL	2.1173 mL
	60 mM	0.0706 mL	0.3529 mL	0.7058 mL	1.7644 mL
	80 mM	0.0529 mL	0.2647 mL	0.5293 mL	1.3233 mL
	100 mM	0.0423 mL	0.2117 mL	0.4235 mL	1.0586 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.