1. Membrane Transporter/Ion Channel
  2. P2X Receptor
  3. P2X7 receptor antagonist-3

P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats.

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P2X7 receptor antagonist-3

P2X7 receptor antagonist-3 Chemische Struktur

CAS. Nr. : 1627900-92-8

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Beschreibung

P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats[1].

IC50 & Target[1]

hP2X7R

4.2 nM (IC50)

rP2X7R

6.8 nM (IC50)

Molekulargewicht

408.76

Formel

C17H12ClF3N6O

CAS. Nr.
SMILES

O=C(N1CC2=C(CC1)N(C3=NC=CC=N3)N=N2)C4=CC=CC(C(F)(F)F)=C4Cl

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

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P2X7 receptor antagonist-3
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