2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Phenibut

Phenibut  (Synonyms: β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid)

Art. -Nr.: HY-108403 Reinheit: 99.88%
COA
SDS
Handling Instructions Technical Support

Phenibut (β-Phenyl-GABA) is a GABA-B agonist. Phenibut acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut has anxiolytic and nootropic (cognition enhancing) effects.

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Phenibut

Phenibut Chemische Struktur

CAS. Nr. : 1078-21-3

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10 mM * 1 mL in Water
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Other Forms of Phenibut:

Phenibut Related Antibodies

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Beschreibung

Phenibut (β-Phenyl-GABA) is a GABA-B agonist[1]. Phenibut acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut has anxiolytic and nootropic (cognition enhancing) effects[2].

IC50 & Target

GABA-B[1][2]
In Vitro

Phenibut is a neuropsychotropic agent. Phenibut also stimulates dopamine receptors and antagonizes β-phenethylamine (PEA), a putative endogenous anxiogenic[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phenibut Related Antibodies
Molekulargewicht

179.22

Formel

C10H13NO2
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CC(CN)C1=CC=CC=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

H2O : 10 mg/mL (55.80 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5797 mL 27.8987 mL 55.7973 mL
5 mM 1.1159 mL 5.5797 mL 11.1595 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Reinheit & Dokumentation

Purity: 99.88%

SDS (393 KB)

COA (250 KB) HNMR (235 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.5797 mL 27.8987 mL 55.7973 mL 139.4934 mL
5 mM 1.1159 mL 5.5797 mL 11.1595 mL 27.8987 mL
10 mM 0.5580 mL 2.7899 mL 5.5797 mL 13.9493 mL
15 mM 0.3720 mL 1.8599 mL 3.7198 mL 9.2996 mL
20 mM 0.2790 mL 1.3949 mL 2.7899 mL 6.9747 mL
25 mM 0.2232 mL 1.1159 mL 2.2319 mL 5.5797 mL
30 mM 0.1860 mL 0.9300 mL 1.8599 mL 4.6498 mL
40 mM 0.1395 mL 0.6975 mL 1.3949 mL 3.4873 mL
50 mM 0.1116 mL 0.5580 mL 1.1159 mL 2.7899 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Phenibut Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenibut1078-21-3β-Phenyl-GABA 4-Amino-3-phenylbutanoic acidGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid Receptorneuropsychotropicβ-phenethylaminePEAendogenousanxiogenicInhibitorinhibitorinhibit

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