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Results for "

pi3kc2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112613
    UCB9608
    1 Publications Verification

    		 PI4K Inflammation/Immunology
    UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor, with an IC50 of 11 nM, selective over PI3KC2 α, β, and γ lipid kinases. UCB9608 improves metabolic stability and exhibits excellent pharmacokinetic profile, acts as a potent immunosuppressive agent .
    UCB9608
  • HY-156371
    MIPS-21335

    		PI3K Cardiovascular Disease Metabolic Disease
    MIPS-21335 is a PI3KC2α inhibitor with an IC50 of 7 nM. MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ, with IC50 values of 43, 140, 386 and 742 nM, respectively. MIPS-21335 has antithrombotic effect. MIPS-21335 can be used for the researches of cardiovascular disease and metabolic disease, such as thrombosis and hyperlipidemia .
    MIPS-21335
  • HY-156406
    PITCOIN4
    1 Publications Verification

    		 PI3K Inflammation/Immunology
    PITCOIN4 is a highly selective Class II Alpha PI3K-C2α inhibitor. PITCOIN4 shows nanomolar inhibition of PI3K-C2α and >100-fold selectivity in a general kinase panel .
    PITCOIN4
  • HY-178371
    PI3KC2γ-IN-1

    		PI3K Metabolic Disease
    PI3KC2γ-IN-1 (Compound 23) is an orally active and selective PI3KC2γ inhibitor (IC50 = 4 nM). PI3KC2γ-IN-1 downregulats the Akt2-glycogen synthase (GS) signaling pathway, ultimately inhibiting the conversion of glucose to glycogen and reduces excessive glycogen accumulation in the liver. PI3KC2γ-IN-1 can significantly inhibit insulin-induced PI(3,4)P2 accumulation in both primary hepatocytes and HepG2 liver cancer cells. PI3KC2γ-IN-1 can be used for the study of glycogen storage diseases (GSDs) .
    PI3KC2γ-IN-1
  • HY-RS10512
    Pik3c2a Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Pik3c2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pik3c2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Pik3c2a Mouse Pre-designed siRNA Set A
    Pik3c2a Mouse Pre-designed siRNA Set A

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