Acyl carrier/ACP protein, S. aureus (P.pastoris, His)

Acyl carrier/ACP protein, S. aureus (P.pastoris, His) is a highly conserved cofactor protein that is required by Type II fatty acid synthases (FASs).

Acyl carrier protein (ACP) is a principal partner in the cytosolic and mitochondrial fatty acid synthesis (FAS) pathways. ACP is evolutionarily conserved small α-helical proteins that present acyl chain intermediates to catalytic sites of enzymes in the fatty acid synthesis (FAS) pathway. The active form holo-ACP serves as FAS platform, using its 4'-phosphopantetheine group to present covalently attached FAS intermediates to the enzymes responsible for the acyl chain elongation process. Both ptFAS and mtFAS systems utilize acyl carrier protein (ACP) as a cofactor protein that shuttles acyl intermediates between active sites of the catalytic components of each FAS system^[1][2].

Staphylococcus aureus

P. pastoris

N-His

P0A001 (1M-77K)

58067086

MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK

Approximately 10.5 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.

• [1]. Ali J Masud, et al. Mitochondrial acyl carrier protein (ACP) at the interface of metabolic state sensing and mitochondrial function. Biochim Biophys Acta Mol Cell Res. 2019 Dec;1866(12):118540.  [Content Brief]

  [2]. Xinyu Fu, et al. Mitochondrial Fatty Acid Synthase Utilizes Multiple Acyl Carrier Protein Isoforms. Plant Physiol. 2020 Jun;183(2):547-557.  [Content Brief]