Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO)

Calcitonin/CALCA protein acts as a vasodilator, dilating different blood vessels, including coronary, cerebral, and systemic vessels. Its presence in the central nervous system suggests its potential role as a neurotransmitter or neuromodulator. Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO) is the recombinant human-derived Calcitonin/CALCA protein, expressed by P. pastoris , with N-SUMO, N-6*His labeled tag.

Calcitonin/CALCA protein, known for its role as a vasodilator, induces dilation in various vessels, including those in the coronary, cerebral, and systemic vasculature. Its presence in the central nervous system suggests potential functions as a neurotransmitter or neuromodulator. Additionally, Calcitonin/CALCA contributes to the elevation of platelet cAMP, indicating its involvement in regulating intracellular signaling pathways. The multifaceted actions of Calcitonin/CALCA underscore its significance in vascular regulation and neurotransmission within the central nervous system.

Human

P. pastoris

N-SUMO;N-6*His

P06881 (A83-F119)

796  [NCBI]

Full Length of Mature Peptide

ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF

22 kDa

≥ 95%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% trehalose, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.

• [1]. /biology-dictionary/km12-cell.html  [Content Brief]