CAMKI gamma/CAMK1G Protein, Human (Active, sf9, His, GST)

The CAMK1G protein is a calcium/calmodulin-dependent protein kinase and a key component of the proposed calcium-triggered signaling cascade. This kinase exhibits the ability to phosphorylate the transcription factor CREB1 in vitro, suggesting its involvement in regulating cellular processes related to gene expression and transcriptional control. CAMKI gamma/CAMK1G Protein, Human (sf9, His, GST) is the recombinant human-derived CAMKI gamma/CAMK1G protein, expressed by Sf9 insect cells , with His, GST labeled tag.

CAMK1G, also known as calcium/calmodulin-dependent protein kinase I gamma, is a crucial member of the CAMK family, participating in a proposed calcium-triggered signaling cascade. This protein exhibits kinase activity, particularly demonstrated in vitro by its phosphorylation of the transcription factor CREB1 (cAMP response element-binding protein 1), suggesting a role in regulating gene expression. The activation of CAMK1G is contingent upon calcium and calmodulin, emphasizing its involvement in intracellular signaling pathways that respond to changes in calcium levels. CAMK1G has potential significance in transducing calcium signals and modulating downstream cellular events through the phosphorylation, contributing to the broader understanding of its functional role in cellular processes.

Human

Sf9 insect cells

His;GST

Q96NX5-1 (M1-M476)

57172  [NCBI]

Full Length of Isoform-1

MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSSPEITITEAPVLDHSVALPALTQLPCQHGRRPTAPGGRSLNCLVNGSLHISSSLVPMHQGSLAAGPCGCCSSCLNIGSKGKSSYCSEPTLLKKANKKQNFKSEVMVPVKASGSSHCRAGQTGVCLIM

≥ 85%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.