2. Recombinant Proteins
  3. CD Antigens Enzymes & Regulators
  4. Endothelial cell CD Proteins Hydrolases (EC 3)
  5. BST1/CD157
  6. CD157 Protein, Rat (HEK293, Fc)

CD157 Protein, Rat (HEK293, Fc)

Cat. No.: HY-P76204
Handling Instructions

CD157 protein catalyzes the synthesis of cADPR from NAD(+) and hydrolyzes cADPR to ADPR. cADPR acts as a second messenger, releasing calcium from intracellular stores. CD157 protein may also contribute to pre-B cell growth. CD157 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD157 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD157 Protein, Rat (HEK293, Fc) is 293 a.a., with molecular weight of ~67 KDa.

For research use only. We do not sell to patients.

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Description

CD157 protein catalyzes the synthesis of cADPR from NAD(+) and hydrolyzes cADPR to ADPR. cADPR acts as a second messenger, releasing calcium from intracellular stores. CD157 protein may also contribute to pre-B cell growth. CD157 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD157 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD157 Protein, Rat (HEK293, Fc) is 293 a.a., with molecular weight of ~67 KDa.
Background

CD157 protein acts as an enzyme that catalyzes the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+) and also hydrolyzes cADPR to ADP-D-ribose (ADPR). Cyclic ADPR functions as a natural second messenger, triggering the release of calcium from intracellular stores and thereby controlling the mobilization of intracellular calcium. Additionally, CD157 protein may play a role in the growth of pre-B cells.
Species

Rat
Source

HEK293
Tag

C-hFc
Accession

Q63072 (M1-E293)
Gene ID

81506  [NCBI]
Molecular Construction
N-term
CD157 (M1-E293)
Accession # Q63072
hFc
C-term
Synonyms
ADP-ribosyl cyclase; BST1; Cyclic ADP-ribose hydrolase 2; CD157
Molecular Weight

Approximately 67 kDa.
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CD157 Protein, Rat (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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