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  5. CD200 Protein, Rhesus Macaque (HEK293, Fc)

CD200 Protein, Rhesus Macaque (HEK293, Fc)

Cat. No.: HY-P76211
Handling Instructions

CD200 protein functions as a costimulator of T-cell proliferation and is implicated in the potential regulation of myeloid cell activity across various tissues. Through their N-terminal Ig-like domains, CD200 interacts with CD200R1, establishing a molecular interaction that likely contributes to the modulation of immune responses and cellular activities. CD200 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD200 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD200 Protein, Rhesus Macaque (HEK293, Fc) is 202 a.a., with molecular weight of ~49.6 KDa.

For research use only. We do not sell to patients.

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Description

CD200 protein functions as a costimulator of T-cell proliferation and is implicated in the potential regulation of myeloid cell activity across various tissues. Through their N-terminal Ig-like domains, CD200 interacts with CD200R1, establishing a molecular interaction that likely contributes to the modulation of immune responses and cellular activities. CD200 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD200 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD200 Protein, Rhesus Macaque (HEK293, Fc) is 202 a.a., with molecular weight of ~49.6 KDa.

Background

The CD200 protein plays a pivotal role in immune modulation, functioning as a costimulatory molecule that promotes T-cell proliferation. Additionally, CD200 is implicated in the potential regulation of myeloid cell activity across various tissues, as suggested by similarity-based inferences. The interaction between CD200 and its receptor, CD200R1, is facilitated through their respective N-terminal Ig-like domains. This interaction likely contributes to the regulatory processes involved in immune responses and myeloid cell function. The engagement of CD200 with CD200R1 underscores its significance in mediating immune cell communication and homeostasis, emphasizing its potential as a key player in immunomodulation.

Species

Rhesus Macaque

Source

HEK293

Tag

C-hFc

Accession

H9EXH3 (Q31-G232)

Gene ID

708110  [NCBI]

Molecular Construction
N-term
CD200 (Q31-G232)
Accession # H9EXH3
hFc
C-term
Synonyms
OX-2 membrane glycoprotein; CD200; MOX1; MOX2; My033
Molecular Weight

Approximately 49.6 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD200 Protein, Rhesus Macaque (HEK293, Fc)
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HY-P76211
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