CD93/C1qR1 Protein, Human (Biotinylated, HEK293, His-Avi)

The CD93/C1qR1 protein is thought to be a receptor or part of a larger complex and plays a crucial role in immune recognition by binding to C1q, mannose-binding lectin (MBL2), and pulmonary surfactant protein A (SPA) . Its interaction with these immune factors suggests a role in coordinating the innate immune response. CD93/C1qR1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD93/C1qR1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD93/C1qR1 Protein, Human (Biotinylated, HEK293, His-Avi) is 559 a.a., with molecular weight of 90-110 kDa.

CD93/C1qR1 Protein, identified as a receptor or a component of a larger receptor complex, plays a crucial role in immune recognition by serving as a binding site for C1q, mannose-binding lectin (MBL2), and pulmonary surfactant protein A (SPA). Its interaction with these immune factors suggests a role in orchestrating innate immune responses. CD93/C1qR1 may also participate in the modulation of phagocytosis in monocytes and macrophages, particularly when interacting with soluble defense collagens. Additionally, it appears to be involved in intercellular adhesion, indicating a potential role in cellular interactions beyond immune recognition. The observed interaction with C1QBP further implies its association with cell surface C1q, highlighting the intricate involvement of CD93/C1qR1 in immune-related processes and suggesting its significance in cellular responses to external challenges.

Human

HEK293

C-Avi;C-His

Q9NPY3 (T22-K580)

22918  [NCBI]

90-110 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.