2. Recombinant Proteins
  3. Others
  4. Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His)

Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His)

Cat. No.: HY-P700440
Handling Instructions Technical Support

Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

사이즈 재고
50 μg   견적 받기  
100 μg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • 제품 설명

제품 설명

Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.
Background

Claudin-18/CLDN18.2 Protein-VLP from Macaca fascicularis belongs to the claudin family of proteins. Claudins are integral membrane proteins known for their role in tight junctions, contributing to the structural and functional integrity of epithelial and endothelial cell layers. In particular, CLDN18.2, found in Macaca fascicularis, is associated with the development and maintenance of tissue barriers. The formation of virus-like particles (VLPs) enhances the potential applications of CLDN18.2 protein, offering a versatile tool in research and therapeutic contexts. The utilization of Macaca fascicularis as the source organism underlines the relevance of this primate species in studying and potentially manipulating claudin-related functions, providing valuable insights into the intricate mechanisms of cellular barrier regulation.
Species

Cynomolgus
Source

HEK293
Tag

N-6*His
Accession

A0A2K5VV62 (M1-V261)
Gene ID

/
Molecular Construction
N-term
6*His
CLDN18 (M1-V261)
Accession # A0A2K5VV62
C-term
Protein Length

Full Length
Synonyms
CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
AA Sequence

MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKTYDGGAHTEDELQSYPSKHDYV

Predicted Molecular Mass
28.7 kDa
Purity

Purity analysis by SDS-PAGE is not available for VLP proteins.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

최근 본 상품:

온라인 문의

Your information is safe with us. * Required Fields.

Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His)

  

Requested Quantity *

고객명 *

 

호칭

메일주소 *

 

전화번호 *

Department

 

회사명 *

City

도

Country or Region *

      

비고

대량구매 문의

Inquiry Information

상품명:
Claudin-18/CLDN18.2 Protein-VLP, Cynomolgus (HEK293, His)
Cat. No.:
HY-P700440
수량:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

상품명

  

Lot #

고객명 *

 

Country or Region *

메일주소 *

     

전화번호 *

 

회사명 *

비고

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.