DEC-205/CD205 Protein, Cynomolgus (HEK293, His)

DEC-205/CD205 Protein, an endocytic receptor, transports captured antigens to a specialized processing compartment, placing it at the forefront of antigen presentation. This role is crucial for immune surveillance and initiating immune responses. DEC-205/CD205's involvement also downregulates B-lymphocyte proliferation, showcasing its regulatory impact on immune cell dynamics and responses. DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DEC-205/CD205 protein, expressed by HEK293 , with C-His labeled tag.

DEC-205/CD205 protein serves as an endocytic receptor, facilitating the transportation of captured antigens from the extracellular space to a specialized antigen-processing compartment. This function positions DEC-205/CD205 at the forefront of antigen presentation, playing a crucial role in immune surveillance and the initiation of immune responses. Moreover, its involvement leads to the downregulation of B-lymphocyte proliferation, highlighting its regulatory impact on immune cell dynamics and responses.

Cynomolgus

HEK293

C-8*His

XP_005573337.2 (S28-D1666)

102120600  [NCBI]

Partial

SGRAANDPFTIVHGNTGKCIKPVYGWIVAEDCDETEDKLWKWVSQHRLFHLHSQKCLGLDITKSVNEVRMFSCDSSVMLWWKCEHHSLYSAARYQLALKNGHGAAISNASDIWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLVDGTWHHDCILDEDHSGPWCATTLNYEYDRMWGICLKPENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCDAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKDFSGDLISIHSLADVEVVVTKLHNEDTKEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGEKLNDTSSDKMCPPNEGWKRHGETCYKIYEDEVPFGTNCNLTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSHGEYNWATVGGTRWSVTFSNWNFLEPASPGGCVAMSTGKSLGKWEVKDCRSFKALSICKKMSRPLEPEEAAPKPDDPCPEGWQSFPTSLSCYKVFHAQRIVRKRNWEEAERFCQALGAHLSSFSRVDEIKEFLHFLTDQFSGQRWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPERAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFAGLKAIKNKIANISGDGQKWWIRINEQPIDDHFTYSRYPWHRFHVTFGEECLYMSAKTWLIDLSKPTDCNTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPMSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYERINKWTDNRELTYSNFHPLLVSRRLRIPENLFEEESHYHCALILNLQKSPFIGTWNFTSCSERHFVSLCQKYSEVKGRQTLQNASETVKYLNNLYKIIPKTLTWHGAQKECLKNNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLEDCVILDTDGFWKTADCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATTLDEVHSKCQKLNPESQILSIRDEKENNFVLEQLLYFNYMASWVTLGITYENNSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTDGFWDIKTFNVIEETLYFHQHSILACKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHDQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSIFDYIPWKGQTSPGNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSHLTYSSRCPTVKENGSRWIQYKGHCYTSDQALHSFSEAKKLCSKHGQSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGIGKCSMLIASNETWKNVECEHGFGRVVCKMPLGPD

Approximately 230-245 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.