1. Recombinant Proteins
  2. Receptor Proteins
  3. Notch family
  4. Delta-like 3 (DLL3)
  5. Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His)

Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P77641
Handling Instructions

Delta-like protein 3/DLL3 stands out as a key regulator of neurogenesis and cell differentiation. As an inhibitor of primary neurogenesis, DLL3 plays a crucial role in guiding neurons along specific differentiation pathways. Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Delta-like protein 3/DLL3 protein, expressed by HEK293 , with N-His labeled tag. The total length of Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His) is 464 a.a., with molecular weight of 52-55 kDa.

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Description

Delta-like protein 3/DLL3 stands out as a key regulator of neurogenesis and cell differentiation. As an inhibitor of primary neurogenesis, DLL3 plays a crucial role in guiding neurons along specific differentiation pathways. Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Delta-like protein 3/DLL3 protein, expressed by HEK293 , with N-His labeled tag. The total length of Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His) is 464 a.a., with molecular weight of 52-55 kDa.

Background

Delta-like protein 3/DLL3 emerges as a key regulator in the intricate landscape of neurogenesis and cellular differentiation. Acting as an inhibitor of primary neurogenesis, DLL3 is believed to play a crucial role in steering neurons along specific differentiation pathways. Its involvement extends beyond neurogenesis, contributing to the formation of somite boundaries during the segmentation of the paraxial mesoderm. Notably, DLL3 exhibits the capability to bind and activate Notch-1 or other Notch receptors, underscoring its significance in orchestrating cellular processes that govern developmental pathways and cellular fate determination.

Species

Cynomolgus

Source

HEK293

Tag

N-His

Accession

A0A2K5WSR4 (A27-R490)

Gene ID

/

Molecular Construction
N-term
His
Dll1 (A27-R490)
Accession # A0A2K5WSR4
C-term
Synonyms
Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3
Molecular Weight

52-55 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Delta-like protein 3/DLL3 Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P77641
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