EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293)

EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with tag free. The total length of EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293) is 265 a.a., with molecular weight of 35-45 kDa.

EpCAM/TROP1 protein functions as a crucial player in multiple biological processes. It serves as a physical homophilic interaction molecule, facilitating communication between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) within the mucosal epithelium, thereby establishing an immunological barrier as the initial defense against mucosal infections. EpCAM/TROP1 also plays a crucial role in regulating the proliferation and differentiation of embryonic stem cells. Additionally, it is involved in the up-regulation of FABP5, MYC, and cyclins A and E, potentially influencing cell cycle progression. EpCAM/TROP1 exists as a monomer and interacts with phosphorylated CLDN7, further highlighting its diverse functional repertoire.

Immobilized Rhesus macaque/Cynomolgus EpCAM, No Tag at 2 μg/mL (100μl/well) on the plate. Dose response curve for Anti-EpCAM Antibody, hFc Tag with the EC₅₀ of 71.8 ng/mL determined by ELISA.

Rhesus Macaque

HEK293

Tag Free

Q1WER1 (M1-K265)

677680  [NCBI]

35-45 kDa

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.