2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. Endothelial cell CD Proteins
  5. CD201/Activated Protein C Receptor
  6. EPCR Protein, Cynomolgus (HEK293, Fc)

EPCR Protein, Cynomolgus (HEK293, Fc)

Cat. No.: HY-P76906
Handling Instructions

EPCR Protein plays a pivotal role in blood coagulation by binding to and enhancing the activation of protein C through interaction with the thrombin-thrombomodulin complex. Its significance lies in regulating coagulation processes and modulating protein C activation, a crucial factor in anticoagulant mechanisms. EPCR Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived EPCR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EPCR Protein, Cynomolgus (HEK293, Fc) is 209 a.a., with molecular weight of 58-68 kDa.

For research use only. We do not sell to patients.

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Description

EPCR Protein plays a pivotal role in blood coagulation by binding to and enhancing the activation of protein C through interaction with the thrombin-thrombomodulin complex. Its significance lies in regulating coagulation processes and modulating protein C activation, a crucial factor in anticoagulant mechanisms. EPCR Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived EPCR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EPCR Protein, Cynomolgus (HEK293, Fc) is 209 a.a., with molecular weight of 58-68 kDa.
Background

The EPCR protein exhibits a pivotal role in blood coagulation by binding to activated protein C and enhancing its activation through interaction with the thrombin-thrombomodulin complex. This participation in the protein C pathway underscores EPCR's significance in regulating coagulation processes, highlighting its ability to modulate the activation of protein C, a key factor in anticoagulant mechanisms.
Species

Cynomolgus
Source

HEK293
Tag

C-hFc
Accession

XP_001100647 (M1-T209)
Gene ID

706040  [NCBI]
Molecular Construction
N-term
EPCR (M1-T209)
Accession # XP_001100647
hFc
C-term
Synonyms
Endothelial Protein C Receptor; Activated Protein C Receptor; APC Receptor; Endothelial Cell Protein C Receptor; CD201; PROCR; EPCR
Molecular Weight

58-68 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

EPCR Protein, Cynomolgus (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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