FAM3D Protein, Mouse (HEK293, Fc)

FAM3D protein is part of the FAM3 family and plays an important role in cell signaling as a transmembrane ligand in the ephrin family.FAM3D interacts with its Eph receptor, initiates bidirectional signaling, regulates multiple cellular processes in development, and is involved in tissue boundary formation, axon guidance, angiogenesis, and synaptic plasticity.FAM3D Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived FAM3D protein, expressed by HEK293 , with C-hFc labeled tag.

FAM3D Protein belongs to the FAM3 family. It is a member of the ephrin family, which consists of proteins that play crucial roles in cellular signaling and communication. FAM3D specifically functions as a transmembrane ligand, interacting with its corresponding Eph receptor to initiate bidirectional signaling events that regulate a wide range of cellular processes. This protein is involved in various developmental processes such as tissue boundary formation, axon guidance, angiogenesis, and synaptic plasticity. Furthermore, FAM3D has been implicated in several pathological conditions, including cancer, cardiovascular diseases, and neurological disorders, thereby making it a potential target for therapeutic intervention.

Mouse

HEK293

C-hFc

P97805 (Y26-M223)

18300  [NCBI]

Full Length of Mature Protein

YTSFSRKTIRLPRWLGITPKDIQTPKSKCGLSKICPNNFFAFKISSGAANVVGPSMCFEDEIIMSPVRNNVGRGLNVALVNGSTGQVMKKDSFDMYSGDPQLLLNFLTEIPDSTLVLVASYDDPGTKMNDKIKTLFSNLGSSYAKQLGFRDSWVFVGAKDLKSKSPYEQFLKNNPETNKYDGWPELLELEGCVPRKVM

Approximately 52-58 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

≥ 90%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.