GMP KGF/FGF-7 Protein, Human (163a.a)

KGF/FGF-7 Protein orchestrates embryonic development, regulating fundamental processes like cell proliferation and differentiation. Its pivotal role extends to normal branching morphogenesis. As a growth factor for keratinocytes, KGF/FGF-7 governs epithelial cell proliferation. Key interactions with FGFBP1 and FGFR2, along with heightened binding affinity through heparan sulfate glycosaminoglycans, underscore KGF/FGF-7's crucial role as a paracrine effector in molecular interactions during embryonic development. GMP KGF/FGF-7 Protein, Human (163a.a) is the recombinant human-derived KGF/FGF-7 protein, expressed by E. coli, with tag free. The total length of GMP KGF/FGF-7 Protein, Human (163a.a) is 163 a.a., with molecular weight of 15-18 kDa.

KGF/FGF-7 Protein assumes a crucial role in orchestrating embryonic development, exhibiting regulatory control over fundamental processes encompassing cell proliferation and differentiation. Its essential contribution extends to the intricate realm of normal branching morphogenesis, where KGF/FGF-7 plays a pivotal role. As a growth factor specifically active on keratinocytes, it emerges as a potential major paracrine effector governing normal epithelial cell proliferation. The protein establishes key interactions, forming complexes with FGFBP1 and FGFR2, and its binding affinity with fibroblast growth factors (FGFs) and their receptors is augmented by heparan sulfate glycosaminoglycans, acting as critical coreceptors in these molecular interactions.

Human

E. coli

Tag Free

P21781 (C32-T194)

2252

15-18 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.