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H2-D1 Protein, Mouse (His-SUMO)

Cat. No.: HY-P71518
Handling Instructions

The H2-D1 protein is a key element of the immune system and is actively involved in the presentation of foreign antigens. As a major histocompatibility complex class I (MHC-I) component, H2-D1 forms a heterodimer with α and β chains and is essential for recognizing and presenting antigen to cytotoxic T cells. H2-D1 Protein, Mouse (His-SUMO) is the recombinant mouse-derived H2-D1 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of H2-D1 Protein, Mouse (His-SUMO) is 287 a.a., with molecular weight of ~49.2 kDa.

For research use only. We do not sell to patients.

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Description

The H2-D1 protein is a key element of the immune system and is actively involved in the presentation of foreign antigens. As a major histocompatibility complex class I (MHC-I) component, H2-D1 forms a heterodimer with α and β chains and is essential for recognizing and presenting antigen to cytotoxic T cells. H2-D1 Protein, Mouse (His-SUMO) is the recombinant mouse-derived H2-D1 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of H2-D1 Protein, Mouse (His-SUMO) is 287 a.a., with molecular weight of ~49.2 kDa.

Background

The H2-D1 Protein plays a crucial role in the immune system by participating in the presentation of foreign antigens. As a key component of the major histocompatibility complex class I (MHC-I), H2-D1 forms a heterodimer with an alpha chain and a beta chain (beta-2-microglobulin). This complex is essential for the recognition and presentation of antigens to cytotoxic T cells, contributing to the surveillance and defense mechanisms of the immune system. Through its involvement in antigen presentation, H2-D1 plays a vital role in the orchestration of immune responses, facilitating the identification and elimination of foreign entities by the adaptive immune system.

Species

Mouse

Source

E. coli

Tag

N-His;N-SUMO

Accession

P01900 (25G-311T)

Gene ID

14964

Molecular Construction
N-term
6*His-SUMO
H2-D1 (25G-311T)
Accession # P01900
C-term
Synonyms
H2-D1; H-2 class I histocompatibility antigen; D-D alpha chain; H-2D(D)
AA Sequence

GSHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWGKEEPPSSTKTNT

Molecular Weight

Approximately 49.2 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

H2-D1 Protein, Mouse (His-SUMO) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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H2-D1 Protein, Mouse (His-SUMO)
Cat. No.:
HY-P71518
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