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  4. IL-21R CD360/IL-21R
  5. IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)

IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)

Cat. No.: HY-P76431
Handling Instructions

Interleukin-21 receptor is a novel class I cytokine receptor that mediates its effects through the interaction with the common g chain (gc), making IL-21 the latest member of the family of gc cytokines, which includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15. IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived IL-21R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 236 a.a., with molecular weight of ~52 KDa.

For research use only. We do not sell to patients.

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Description

Interleukin-21 receptor is a novel class I cytokine receptor that mediates its effects through the interaction with the common g chain (gc), making IL-21 the latest member of the family of gc cytokines, which includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15. IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived IL-21R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 236 a.a., with molecular weight of ~52 KDa.

Background

Interleukin-21 receptor is a novel class I cytokine receptor that mediates its effects through the interaction with the common g chain (gc), making IL-21 the latest member of the family of gc cytokines, which includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15. Interleukin-21 receptor enables cytokine receptor activity and protein binding. Interleukin-21 receptor is involved in cytokine-mediated signaling pathway and in immunoglobulin mediated immune response. Interleukin-21 receptor is located in external side of plasma membrane[1][2][3].

Species

Rhesus Macaque

Source

HEK293

Tag

C-hFc

Accession

XP_005591578 (M1-P236)

Gene ID

102135042  [NCBI]

Molecular Construction
N-term
IL-21R (M1-P236)
Accession # XP_005591578
hFc
C-term
Synonyms
Interleukin-21 receptor; IL-21 receptor; IL-21R; CD360; Nilr
Molecular Weight

Approximately 52 kDa.

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)
Cat. No.:
HY-P76431
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