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Neurotensin Protein, Human (HEK293, Fc)

Cat. No.: HY-P73743
COA Handling Instructions

Neurotensin, a neuropeptide, potentially modulates fat metabolism through endocrine or paracrine mechanisms, inducing smooth muscle contraction. It interacts with specific receptors like NTSR1 and binds to proteins, including SORT1 and SORL1, indicating involvement in diverse cellular processes and potential regulatory functions in fat metabolism. Neurotensin Protein, Human (HEK293, Fc) is the recombinant human-derived Neurotensin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Neurotensin Protein, Human (HEK293, Fc) is 148 a.a., with molecular weight of ~41 kDa.

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Description

Neurotensin, a neuropeptide, potentially modulates fat metabolism through endocrine or paracrine mechanisms, inducing smooth muscle contraction. It interacts with specific receptors like NTSR1 and binds to proteins, including SORT1 and SORL1, indicating involvement in diverse cellular processes and potential regulatory functions in fat metabolism. Neurotensin Protein, Human (HEK293, Fc) is the recombinant human-derived Neurotensin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Neurotensin Protein, Human (HEK293, Fc) is 148 a.a., with molecular weight of ~41 kDa.

Background

Neurotensin, a neuropeptide, is implicated in potential endocrine or paracrine modulation of fat metabolism and is known to induce smooth muscle contraction. The multifaceted roles of neurotensin include interactions with specific receptors such as NTSR1, along with binding to proteins like SORT1 and SORL1, suggesting its involvement in diverse cellular processes and potential regulatory functions in fat metabolism.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

P30990 (M1-L148)

Gene ID
Molecular Construction
N-term
Neurotensin (M1-L148)
Accession # P30990
hFc
C-term
Synonyms
Neurotensin; neuromedin N; NmN-125; NmN; NTS
Molecular Weight

Approximately 41 kDa

Purity

Greater than 85% as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Neurotensin Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Neurotensin Protein, Human (HEK293, Fc)
Cat. No.:
HY-P73743
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