RPS19 Protein, Human
Based on 1 Customer Validation
RPS19 is an important small ribosomal subunit component that is essential for protein synthesis. Within the SSU processome, it contributes to the processing and maturation of the 40S ribosomal subunit and participates in SSU processome assembly in the nucleolus. RPS19 Protein, Human is the recombinant human-derived RPS19 protein, expressed by E. coli , with tag free.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
RPS19 is an important small ribosomal subunit component that is essential for protein synthesis. Within the SSU processome, it contributes to the processing and maturation of the 40S ribosomal subunit and participates in SSU processome assembly in the nucleolus. RPS19 Protein, Human is the recombinant human-derived RPS19 protein, expressed by E. coli , with tag free.
RPS19, an integral component of the small ribosomal subunit, plays a crucial role in the synthesis of proteins within the cell. As part of the small subunit (SSU) processome, RPS19 contributes to the processing and maturation of 40S ribosomal subunits, participating in the intricate assembly of the SSU processome in the nucleolus. Within this process, various ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins collaborate to facilitate RNA folding, modifications, rearrangements, cleavage, and targeted degradation of pre-ribosomal RNA by the RNA exosome. Moreover, RPS19 interacts with RPS19BP1, directly mediating the integration of RPS19 in state post-A1, highlighting its involvement in the intricate molecular events underlying ribosomal subunit maturation.
Technical Parameters
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Species Human
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Source E. coli
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Tag Tag Free
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Accession
P39019 (P2-H145)
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Molecular Construction
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N-term
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RPS19 (P2-H145)
Accession # P39019 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
RPS19; S19; Prev. LOH19CR1; Loss Of Heterozygosity On Chromosome 19, Region 1; Small Ribosomal Subunit Protein ES19; Loss Of Heterozygosity, 19, Chromosomal Region 1; 40S Ribosomal Protein S19; Diamond-Blackfan Anemia; ES19; DBA1; Ribosomal Protein S19; D
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AA Sequence
PGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH
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Predicted Molecular Mass
16.1 kDa
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Molecular Weight
Approximately 16 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, 1 mM EDTA, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US;may vary elsewhere.
Documentation
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Data Sheet (235 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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