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RPS19 Protein, Human

Cat. No.: HY-P71265
COA Handling Instructions

RPS19 is an important small ribosomal subunit component that is essential for protein synthesis. Within the SSU processome, it contributes to the processing and maturation of the 40S ribosomal subunit and participates in SSU processome assembly in the nucleolus. RPS19 Protein, Human is the recombinant human-derived RPS19 protein, expressed by E. coli , with tag free. The total length of RPS19 Protein, Human is 144 a.a., with molecular weight of ~16.0 kDa.

For research use only. We do not sell to patients.

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50 μg $360 In-stock
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Description

RPS19 is an important small ribosomal subunit component that is essential for protein synthesis. Within the SSU processome, it contributes to the processing and maturation of the 40S ribosomal subunit and participates in SSU processome assembly in the nucleolus. RPS19 Protein, Human is the recombinant human-derived RPS19 protein, expressed by E. coli , with tag free. The total length of RPS19 Protein, Human is 144 a.a., with molecular weight of ~16.0 kDa.

Background

RPS19, an integral component of the small ribosomal subunit, plays a crucial role in the synthesis of proteins within the cell. As part of the small subunit (SSU) processome, RPS19 contributes to the processing and maturation of 40S ribosomal subunits, participating in the intricate assembly of the SSU processome in the nucleolus. Within this process, various ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins collaborate to facilitate RNA folding, modifications, rearrangements, cleavage, and targeted degradation of pre-ribosomal RNA by the RNA exosome. Moreover, RPS19 interacts with RPS19BP1, directly mediating the integration of RPS19 in state post-A1, highlighting its involvement in the intricate molecular events underlying ribosomal subunit maturation.

Species

Human

Source

E. coli

Tag

Tag Free

Accession

P39019 (P2-H145)

Gene ID
Molecular Construction
N-term
RPS19 (P2-H145)
Accession # P39019
C-term
Synonyms
40S Ribosomal Protein S19; RPS19
AA Sequence

PGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH

Molecular Weight

Approximately 16.0 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, 1 mM EDTA, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US;may vary elsewhere.

Documentation

RPS19 Protein, Human Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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RPS19 Protein, Human
Cat. No.:
HY-P71265
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