SLC52A1 Protein, Human (Sf9, His, MBP, FLAG)

The SLC52A1 protein acts as a plasma membrane transporter, promoting cellular uptake of vitamin B2/riboflavin that is critical for metabolic responses. Humans rely on external sources to obtain B2, which emphasizes its importance. SLC52A1 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC52A1 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC52A1 Protein, Human (Sf9, His, MBP, FLAG) is 447 a.a., .

The SLC52A1 Protein operates as a plasma membrane transporter, facilitating the cellular uptake of the water-soluble vitamin B2/riboflavin, which plays a crucial role in biochemical oxidation-reduction reactions associated with carbohydrate, lipid, and amino acid metabolism. Notably, humans are reliant on external sources for vitamin B2/riboflavin as they lack the ability to synthesize it endogenously, emphasizing the significance of intestinal absorption for obtaining this essential nutrient. In addition to its role in vitamin transport, SLC52A1 may function as a cell receptor for retroviral envelopes, particularly those resembling the porcine endogenous retrovirus (PERV-A), suggesting potential implications in microbial infection. This dual functionality highlights the diverse roles of SLC52A1 in cellular processes, ranging from fundamental metabolic pathways to interactions with retroviral elements.

Human

Sf9 insect cells

N-MBP;C-Flag;N-8*His

Q9NWF4 (A2-P448)

55065

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.