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  5. Syndecan-1/CD138 Protein, Mouse (HEK293, Fc)

Syndecan-1/CD138 Protein, Mouse (HEK293, Fc)

Cat. No.: HY-P77853
Handling Instructions

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix. It collaborates with SDCBP and PDCD6IP to regulate exosome biogenesis. It induces its own expression in dental cells through an MSX1 pathway. It interacts with CDCP1 and TIAM1, binding to the PDZ domain of TIAM1. It also interacts with MDK, impacting cellular processes. Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) is 233 a.a., with molecular weight of 85-110 kDa.

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Description

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix. It collaborates with SDCBP and PDCD6IP to regulate exosome biogenesis. It induces its own expression in dental cells through an MSX1 pathway. It interacts with CDCP1 and TIAM1, binding to the PDZ domain of TIAM1. It also interacts with MDK, impacting cellular processes. Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) is 233 a.a., with molecular weight of 85-110 kDa.

Background

Syndecan-1/CD138 Protein is a cell surface proteoglycan that incorporates both heparan sulfate and chondroitin sulfate, playing a crucial role in connecting the cytoskeleton to the interstitial matrix. It collaborates with SDCBP and PDCD6IP to regulate the biogenesis of exosomes. Additionally, Syndecan-1/CD138 Protein has the ability to trigger its own expression in dental mesenchymal cells and neighboring dental epithelial cells through an MSX1-mediated pathway. It interacts with CDCP1 and TIAM1, specifically binding to the PDZ domain of TIAM1 via its C-terminus. Furthermore, Syndecan-1/CD138 Protein interacts with MDK, contributing to various cellular processes.

Species

Mouse

Source

HEK293

Tag

C-hFc

Accession

P18828 (Q23-G255)

Gene ID

20969  [NCBI]

Molecular Construction
N-term
CD138 (Q23-G255)
Accession # P18828
hFc
C-term
Synonyms
Syndecan-1; SYND1; CD138; SDC1; SDC; SDC1
Molecular Weight

85-110 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Syndecan-1/CD138 Protein, Mouse (HEK293, Fc)
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HY-P77853
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