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usp8-protein-human-sf9-his

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  • HY-P74479
    USP5 Protein, Human (sf9, His)

    Ubiquitin carboxyl-terminal hydrolase 5; Isopeptidase T; usp5; ISOT

    		Human Sf9 insect cells
    USP5 protein selectively cleaves branched multiubiquitin polymers, favoring 'Lys-48'-linked polyubiquitin disassembly. It exhibits lower affinity for linear and 'Lys-63'-linked polyubiquitin. USP5 knockdown leads to p53/TP53 accumulation, enhancing p53/TP53 transcriptional activity, as unanchored polyubiquitin competes with ubiquitinated p53/TP53 for proteasomal recognition, unlike MDM2. USP5 Protein, Human (sf9, His) is the recombinant human-derived USP5 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of USP5 Protein, Human (sf9, His) is 835 a.a., with molecular weight of ~100 kDa.
  • HY-P701447
    USP28 Protein, Human (Sf9, His)

    usp28; Ubiquitin carboxyl-terminal hydrolase 28; Deubiquitinating enzyme 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28

    		 Human Sf9 insect cells
    The USP28 protein serves as a deubiquitinase and plays a key role in the DNA damage response checkpoint and the stability of the MYC proto-oncogene. It selectively deubiquitinates DNA damage pathway proteins such as CLSPN, thereby regulating apoptosis. USP28 Protein, Human (Sf9, His) is the recombinant human-derived USP28 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of USP28 Protein, Human (Sf9, His) is 1076 a.a., .
  • HY-P701455
    USP37 Protein, Human (Sf9, His)

    usp37; Ubiquitin carboxyl-terminal hydrolase 37; Deubiquitinating enzyme 37; Ubiquitin thioesterase 37; Ubiquitin-specific-processing protease 37

    		 Human Sf9 insect cells
    The USP37 protein is a multifunctional deubiquitinase that regulates critical cellular processes. During the G1/S transition, it deubiquitinates cyclin A, promotes S phase entry, and enhances activity through Ser-628 phosphorylation. USP37 Protein, Human (Sf9, His) is the recombinant human-derived USP37 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of USP37 Protein, Human (Sf9, His) is 978 a.a., .
  • HY-P701420
    USP47 Protein, Human (Sf9, His, FLAG)

    usp47; Ubiquitin carboxyl-terminal hydrolase 47; Deubiquitinating enzyme 47; Ubiquitin thioesterase 47; Ubiquitin-specific-processing protease 47

    		 Human Sf9 insect cells
    The USP47 protein is a ubiquitin-specific protease that deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizes POLB, and regulates base excision repair (BER). In addition to DNA repair, USP47 is an important regulator of cell growth and genome integrity. USP47 Protein, Human (Sf9, His, FLAG) is the recombinant human-derived USP47 protein, expressed by Sf9 insect cells , with C-Flag, N-8*His labeled tag. The total length of USP47 Protein, Human (Sf9, His, FLAG) is 1374 a.a., .
  • HY-P701425
    USP51 Protein, Human (Sf9, His, FLAG)

    usp51; Ubiquitin carboxyl-terminal hydrolase 51; Deubiquitinating enzyme 51; Ubiquitin thioesterase 51; Ubiquitin-specific-processing protease 51

    		 Human Sf9 insect cells
    The USP51 protein uniquely regulates the DNA damage response by deubiquitinating the "Lys-14" (H2AK13Ub) and "Lys-16" (H2AK15Ub) residues of histone H2A at double-strand breaks. After DNA damage, USP51 is recruited to chromatin and regulates TP53BP1 and BRCA1 assembly/disassembly, which is critical for DNA repair. USP51 Protein, Human (Sf9, His, FLAG) is the recombinant human-derived USP51 protein, expressed by Sf9 insect cells , with N-Flag, N-8*His labeled tag. The total length of USP51 Protein, Human (Sf9, His, FLAG) is 344 a.a., .
  • HY-P702584
    USP10 Protein, Human (Sf9, His, GST)

    usp10; Ubiquitin carboxyl-terminal hydrolase 10; Deubiquitinating enzyme 10; Ubiquitin thioesterase 10; Ubiquitin-specific-processing protease 10

    		 Human Sf9 insect cells
  • HY-P701412
    USP16 Protein, Human (Sf9, His)

    usp16; Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-processing protease UBP-M; Ubiquitin-specific-processing protease 16

    		 Human Sf9 insect cells
    The USP16 protein is a specific deubiquitinase that targets "Lys-120" of histone H2A (H2AK119Ub), a tag associated with epigenetic transcriptional repression. By catalytically removing this ubiquitin moiety, USP16 acts as a coactivator, promoting subsequent phosphorylation of histone H3 (H3S10ph) 'Ser-11' to achieve mitotic chromosome segregation. USP16 Protein, Human (Sf9, His) is the recombinant human-derived USP16 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of USP16 Protein, Human (Sf9, His) is 822 a.a., .
  • HY-P701451
    USP30 Protein, Human (Sf9, His)

    usp30; Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme 30; Ubiquitin thioesterase 30; Ubiquitin-specific-processing protease 30; Ub-specific protease 30

    		 Human Sf9 insect cells
    USP30 protein is anchored on the outer mitochondrial membrane and severely inhibits mitophagy by antagonizing Parkin (PRKN). Hydrolyzing ubiquitin on RHOT1/MIRO1 and target proteins such as TOMM20 and USP30 blocks Parkin-mediated mitophagy, thereby regulating the clearance of damaged mitochondria. USP30 Protein, Human (Sf9, His) is the recombinant human-derived USP30 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of USP30 Protein, Human (Sf9, His) is 461 a.a., .

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