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FZD3

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Cat. No. Compare Product Name Species Source
  • HY-P79115
    Frizzled-9 Protein, Mouse (HEK293, mFc)

    Frizzled-9; FZD9; Fz-9; mFz3; mFz9; CD349; FZD3

    		Mouse HEK293
    Frizzled-9, a WNT2 receptor, crucially activates the beta-catenin pathway, involving disheveled protein activation, GSK-3 kinase inhibition, nuclear beta-catenin accumulation, and Wnt target gene activation. Beyond canonical signaling, it negatively regulates acetylcholine receptor clustering in neuromuscular junction assembly and influences neural progenitor cell viability by regulating the cell cycle. In hippocampal development, Frizzled-9 regulates neuroblast proliferation and apoptosis. Additionally, it plays a pivotal role in bone dynamics, modulating bone formation and regeneration through non-canonical Wnt signaling pathways. Frizzled-9 Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived Frizzled-9 protein, expressed by HEK293, with C-mFc labeled tag. The total length of Frizzled-9 Protein, Mouse (HEK293, mFc) is 163 a.a., with molecular weight of 52-61 kDa.

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