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SIGIRR

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P74547
    SIGIRR Protein, Mouse (HEK293, His)

    Single Ig IL-1-related receptor; Toll/interleukin-1 receptor 8; TIR8

    		 Mouse HEK293
    SIGIRR protein negatively regulates the Toll-like pathway and IL-1R pathway by inhibiting the recruitment of TLR4. SIGIRR disrupts Il1R1 and IL1RAP heterodimerization through its extracellular domain. SIGIRR Protein, Mouse (HEK293, His-hFc) is the recombinant mouse-derived SIGIRR protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of SIGIRR Protein, Mouse (HEK293, His-hFc) is 117 a.a., with molecular weight of 60-65 kDa.

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