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104113-71-5

" in MedChemExpress (MCE) Product Catalog:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-112538
    1-(1-Naphthyl)piperazine hydrochloride

    1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride

    		 5-HT Receptor Apoptosis Inflammation/Immunology Cancer
    1-1-Naphthylpiperazine hydrochloride (1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride) is a serotonergic derivative of quipazine, which is both an agonist for 5-HT1A receptor and an antagonist for 5-HT2A receptor. 1-1-Naphthylpiperazine hydrochloride induces cell apoptosis. 1-1-Naphthylpiperazine hydrochloride prevents the immunosuppression and photocarcinogenesis .
    1-(1-Naphthyl)piperazine hydrochloride
  • HY-W130288
    1-(1-Naphthyl)piperazine

    		5-HT Receptor Adenylate Cyclase Apoptosis Reactive Oxygen Species (ROS) Cancer
    1-(1-Naphthyl)piperazine is a 5-HT receptor modulator that acts as both a 5-HT2A receptor antagonist and 5-HT1A receptor agonist, and binds to human 5-HT6 receptor with a Ki of 120 nM. 1-(1-Naphthyl)piperazine partially inhibits forskolin-stimulated adenylate cyclase activity in calf substantia nigra. 1-(1-Naphthyl)piperazine inhibits UV-induced immunosuppression. 1-(1-Naphthyl)piperazine induces S-phase cell cycle delay, apoptosis and increases ROS levels, leading to inhibit MNT-1 cell proliferation. 1-(1-Naphthyl)piperazine can be used for melanoma research .
    1-(1-Naphthyl)piperazine

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