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Results for "

4′‐BR

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Peptides

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124113

    4′‐BR

    Sirtuin Apoptosis Cancer
    4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling .
    <em>4</em>'-Bromo-resveratrol
  • HY-130591

    ADC Linker PROTAC Linkers Cancer
    Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-PEG<em>4-Br</em>
  • HY-130161

    ADC Linker PROTAC Linkers Cancer
    m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency . m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
    m-PEG<em>4-Br</em>
  • HY-121845

    Others Metabolic Disease
    4-Br-Bnlm is a selective inhibitor of glucose-regulated protein 94 (Grp94) with an EC50 value of 0.96 µM. 4-Br-Bnlm reduces the levels of mutant myocilin proteins as well as wild-type myocilin misfold in cells. 4-Br-Bnlm promotes the clearance of toxic formsof myocilin and reduces myocilin toxicity .
    <em>4-Br</em>-Bnlm
  • HY-W007803

    PROTAC Linkers Cancer
    Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Boc-NH-C<em>4-Br</em>
  • HY-W011178

    Amino Acid Derivatives Others
    Boc-Phe(4-Br)-OH is a phenylalanine derivative .
    Boc-Phe(<em>4-Br</em>)-OH
  • HY-W013726

    Amino Acid Derivatives Others
    Fmoc-Phe(4-Br)-OH is a phenylalanine derivative that can be used for compound synthesis .
    Fmoc-Phe(<em>4-Br</em>)-OH
  • HY-151190

    S1024

    Histone Demethylase Cancer
    cis-4-Br-2,5-F2-PCPA (S1024) is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a Ki value of 94 nM instead of 8.4 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, cis-4-Br-2,5-F2-PCPA inhibits LSD1 cell proliferation and by increasing the level of dimethylated histone H3 at K4 (H3K4) in CCRF-CEM cells .
    cis-<em>4-Br</em>-2,5-F2-PCPA
  • HY-138486

    PROTAC Linkers Cancer
    Br-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Br-PEG<em>4</em>-acid
  • HY-130512

    PROTAC Linkers Cancer
    Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Br-PEG<em>4</em>-OH
  • HY-138372

    PROTAC Linkers Cancer
    Br-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Br-PEG<em>4</em>-THP
  • HY-138450

    PROTAC Linkers Cancer
    Br-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Br-PEG<em>4</em>-methyl acetate

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