Fmoc-Phe(4-Br)-OH
Based on 1 Customer Validation
Fmoc-Phe(4-Br)-OH is a widely used amino acid derivative. Fmoc-Phe(4-Br)-OH can be used in the synthesis of compounds and for the study of protein-protein interactions and the development of biomaterials. Fmoc-Phe(4-Br)-OH can be used in peptide synthesis to incorporate phenylalanine bromide into the peptide chain.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 198561-04-5
- Formula: C24H20BrNO4
- Molecular Weight:466.32
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Fmoc-Phe (4-Br)-OH is a versatile amino acid derivative. Fmoc-Phe (4-Br)-OH can be used for compound synthesis, as well as for studies on protein interactions and the development of biomaterials. Fmoc-Phe (4-Br)-OH is applicable to peptide synthesis for the incorporation of brominated phenylalanine into peptide chains[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 198561-04-5
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Appearance Solid
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Molecular Weight 466.32
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Formula C24H20BrNO4
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (107.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Qiao JX, et al. Synthesis of Fmoc-Protected Arylphenylalanines (Bip Derivatives) via Nonaqueous Suzuki-Miyaura Cross-Coupling Reactions. J Org Chem. 2016;81(19):9499-9506. [Content Brief]
[2]. Wiedemeyer SJA, et al. Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin. ChemMedChem. 2024;19(23):e202400360. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1445 mL | 10.7223 mL | 21.4445 mL | 53.6113 mL |
| 5 mM | 0.4289 mL | 2.1445 mL | 4.2889 mL | 10.7223 mL | |
| 10 mM | 0.2144 mL | 1.0722 mL | 2.1445 mL | 5.3611 mL | |
| 15 mM | 0.1430 mL | 0.7148 mL | 1.4296 mL | 3.5741 mL | |
| 20 mM | 0.1072 mL | 0.5361 mL | 1.0722 mL | 2.6806 mL | |
| 25 mM | 0.0858 mL | 0.4289 mL | 0.8578 mL | 2.1445 mL | |
| 30 mM | 0.0715 mL | 0.3574 mL | 0.7148 mL | 1.7870 mL | |
| 40 mM | 0.0536 mL | 0.2681 mL | 0.5361 mL | 1.3403 mL | |
| 50 mM | 0.0429 mL | 0.2144 mL | 0.4289 mL | 1.0722 mL | |
| 60 mM | 0.0357 mL | 0.1787 mL | 0.3574 mL | 0.8935 mL | |
| 80 mM | 0.0268 mL | 0.1340 mL | 0.2681 mL | 0.6701 mL | |
| 100 mM | 0.0214 mL | 0.1072 mL | 0.2144 mL | 0.5361 mL |