Boc-NH-C4-Br
Based on 1 publication(s) in Google Scholar
Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 164365-88-2
- Formula: C9H18BrNO2
- Molecular Weight:252.15
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Boc-NH-C4-Br
MoreAll PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 164365-88-2
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Appearance <30°C Solid,>32°C Liquid
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Molecular Weight 252.15
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Formula C9H18BrNO2
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)NCCCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
DMSO : 100 mg/mL (396.59 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9659 mL | 19.8295 mL | 39.6589 mL | 99.1473 mL |
| 5 mM | 0.7932 mL | 3.9659 mL | 7.9318 mL | 19.8295 mL | |
| 10 mM | 0.3966 mL | 1.9829 mL | 3.9659 mL | 9.9147 mL | |
| 15 mM | 0.2644 mL | 1.3220 mL | 2.6439 mL | 6.6098 mL | |
| 20 mM | 0.1983 mL | 0.9915 mL | 1.9829 mL | 4.9574 mL | |
| 25 mM | 0.1586 mL | 0.7932 mL | 1.5864 mL | 3.9659 mL | |
| 30 mM | 0.1322 mL | 0.6610 mL | 1.3220 mL | 3.3049 mL | |
| 40 mM | 0.0991 mL | 0.4957 mL | 0.9915 mL | 2.4787 mL | |
| 50 mM | 0.0793 mL | 0.3966 mL | 0.7932 mL | 1.9829 mL | |
| 60 mM | 0.0661 mL | 0.3305 mL | 0.6610 mL | 1.6525 mL | |
| 80 mM | 0.0496 mL | 0.2479 mL | 0.4957 mL | 1.2393 mL | |
| 100 mM | 0.0397 mL | 0.1983 mL | 0.3966 mL | 0.9915 mL |
Boc-NH-C4-Br Related Classifications
HY-W007803 Related Classifications
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