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693222-51-4

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112477A
    (E/Z)-Chk2-IN-1

    (E/Z)-Hymenialdisine analogue-1

    		 Checkpoint Kinase (Chk) Casein Kinase MEK PKC Cancer
    (E/Z)-Chk2-IN-1 ((E/Z)-Hymenialdisine analogue-1) (Compound 1) is a potent and selective cell cycle kinase Chk2 inhibitor with an IC50 of 8 nM. (E/Z)-Chk2-IN-1 exhibits low inhibitory activity against other kinases (such as CK1δ, MEK1, and PKCα/βⅡ) with IC50 values both >89 nM. (E/Z)-Chk2-IN-1 can be used for the research of cancer .
    (E/Z)-Chk2-IN-1

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