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Bile pigment

" in MedChemExpress (MCE) Product Catalog:

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Biochemical Assay Reagents

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N11424
    Bilirubin diglucuronide

    		Drug Metabolite Glycosyltransferase Metabolic Disease
    Bilirubin diglucuronide is a bilirubin glycoside conjugate with a 1-O-acyl β-D-glucuronide structure. Bilirubin diglucuronide is the major conjugated bilirubin (HY-N0323) and predominant pigment excreted in the bile of adult humans, rats, dogs and cats. Bilirubin diglucuronide is mainly synthesized via UDP-glucuronosyltransferase-mediated transfer of glucuronic acid from UDP-glucuronic acid to bilirubin monoglucuronide, or via enzymatic disproportionation of two moles of bilirubin monoglucuronide (predominantly producing the IXα configuration). In addition, Bilirubin diglucuronide can also be synthesized from bilirubin or its monoglucuronide in a UDP-glucuronic acid-dependent manner. Pretreatment with phenobarbital significantly enhances the formation process of Bilirubin diglucuronide .
    Bilirubin diglucuronide
  • HY-159669
    Stercobilin hydrochloride (mixture of isomers)

    		HIV Protease Infection Inflammation/Immunology
    Stercobilin hydrochloride (amixture of isomers) is a bile pigment metabolized by gut bacteria, and it's also an HIV protease inhibitor, with a Ki of 4 μM. Stercobilin hydrochloride (a mixture of isomers) can induce pro-inflammatory activity in mouse macrophage RAW264 cells, including the production of TNF-α and IL-1β. Stercobilin hydrochloride (a mixture of isomers) can be used in studies of inflammation and viral infections .
    Stercobilin hydrochloride (mixture of isomers)

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