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Results for "

Bim-IN-1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115930
    Bim-IN-1

    		Bcl-2 Family Cardiovascular Disease
    Bim-IN-1 is a potent Bim expression inhibitor. Bim-IN-1 reduces Bim expression levels and has little inhibitory effect upon protein kinase A activity and minimal toxicity [1].
    Bim-IN-1
  • HY-W008325
    Boc-L-Dap-OH

    		Amino Acid Derivatives Others
    Boc-L-Dap-OH is a Boc-protected derivative of L-2,3-diaminopropionic acid. Boc-L-Dap-OH is an important chiral amino acid derivative. Boc-L-Dap-OH can be generated via the Hofmann rearrangement of Boc-L-asparagine. Boc-L-Dap-OH serves as a starting material for the preparation of BIM analogs .
    Boc-L-Dap-OH
  • HY-W016510
    Benzenesulfonate sodium

    		Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium
  • HY-W016510R
    Benzenesulfonate sodium (Standard)

    		Reference Standards Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate (sodium) (Standard) is an analytical standard for Benzenesulfonate sodium (HY-W016510). This product is intended for research and analytical applications. Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium (Standard)
  • HY-181673
    ICD inducer-2

    		Microtubule/Tubulin Apoptosis Bcl-2 Family Caspase PARP Cancer
    ICD inducer-2 is a immunogenic cell death inducer. ICD inducer-2 binds to the colchicine binding site on tubulin to inhibit tubulin polymerization. ICD inducer-2 exhibits broad-spectrum antiproliferative activity across multiple cancer cell lines. ICD inducer-2 inhibits cells migration, causes G2/M phase and induces apoptosis. ICD inducer-2 promotes infiltration of CD4+ and CD8+ T cells into the tumor microenvironment. ICD inducer-2 downregulates antiapoptotic protein Bcl-2, upregulates proapoptotic proteins Bax and Bim-1, and increases cleaved caspase 3, cleaved caspase 9, and cleaved PARP levels. ICD inducer-2 overcomes paclitaxel resistance in xenograft models and achieves tumor growth inhibition. ICD inducer-2 can be used for the research of cancer, such as lung carcinoma [1].
    ICD inducer-2

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