Boc-L-Dap-OH
Based on 1 Customer Validation
Boc-L-Dap-OH is a Boc-protected derivative of L-2,3-diaminopropionic acid. Boc-L-Dap-OH is an important chiral amino acid derivative. Boc-L-Dap-OH can be generated via the Hofmann rearrangement of Boc-L-asparagine. Boc-L-Dap-OH serves as a starting material for the preparation of BIM analogs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 73259-81-1
- Formula: C8H16N2O4
- Molecular Weight:204.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
BIM compounds are a class of 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-based heterocyclic dipeptides, and are among the few known small-molecule tool compounds that can penetrate cell membranes and preferentially silence Gαq proteins. Their core representative molecules are the monomer BIM-46174 and its dimer BIM-46187 (HY-10499)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 73259-81-1
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Appearance Solid
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Molecular Weight 204.23
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Formula C8H16N2O4
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Color White to off-white
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SMILES
O=C(O)[C@H](CN)NC(OC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 10 mg/mL (48.96 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8964 mL | 24.4822 mL | 48.9644 mL | 122.4110 mL |
| 5 mM | 0.9793 mL | 4.8964 mL | 9.7929 mL | 24.4822 mL | |
| 10 mM | 0.4896 mL | 2.4482 mL | 4.8964 mL | 12.2411 mL | |
| 15 mM | 0.3264 mL | 1.6321 mL | 3.2643 mL | 8.1607 mL | |
| 20 mM | 0.2448 mL | 1.2241 mL | 2.4482 mL | 6.1206 mL | |
| 25 mM | 0.1959 mL | 0.9793 mL | 1.9586 mL | 4.8964 mL | |
| 30 mM | 0.1632 mL | 0.8161 mL | 1.6321 mL | 4.0804 mL | |
| 40 mM | 0.1224 mL | 0.6121 mL | 1.2241 mL | 3.0603 mL |