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Results for "

CD300LF

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

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  • HY-P76793
    CD300LF Protein, Mouse (HEK293, Fc)

    CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; CD300f

    		 Mouse HEK293
    CD300LF protein, also known as DEC-205/CD205, directs antigens to an antigen-processing compartment. It inhibits myeloid and mast cells, promoting phagocytosis of apoptotic cells. It maintains immune homeostasis by enhancing macrophage-mediated efferocytosis and inhibiting dendritic cell-mediated efferocytosis. It binds to ceramide ligands, regulating mast cell activation and allergic responses. It enhances IL-4 and IL-13 signaling and inhibits Toll-like receptor signaling and osteoclast formation. It induces macrophage cell death, acts as a receptor for murine norovirus, and determines viral tropism. CD300LF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD300LF protein, expressed by HEK293, with C-mFc labeled tag. The total length of CD300LF Protein, Mouse (HEK293, Fc) is 174 a.a., with molecular weight of ~45.3 KDa.
  • HY-P71595
    CD300LF Protein, Human (His)

    CD300 antigen like family member; CD300 antigen-like family member F; CD300 molecule like family member f; CD300f; CD300LF; CLM; CLM-1; CLM1; CMRF35-like molecule 1; IGSF; IgSF13; Inhibitory receptor IREM1; IREM; IREM-1; IREM1; Nepmucin; NK inhibitory receptor; NKIR; TREM

    		 Human E. coli
    CD300LF Protein functions as a versatile immune regulator, acting as an inhibitory receptor for myeloid and mast cells. It plays a crucial role in immune homeostasis by positively regulating apoptotic cell phagocytosis through binding to phosphatidylserine. CD300LF also acts as a negative regulator of mast cell activation and allergic responses by binding to ceramide and sphingomyelin. It may enhance IL-4 and IL-13 signaling and negatively regulates TLR signaling. Additionally, CD300LF inhibits osteoclast formation and induces macrophage cell death. CD300LF Protein, Human (His) is the recombinant human-derived CD300LF protein, expressed by E. coli, with N-6*His labeled tag. The total length of CD300LF Protein, Human (His) is 137 a.a., with molecular weight of ~21 kDa.
  • HY-P71561
    CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO)

    CD300LF; Clm1CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; CD antigen CD300f

    		 Rat E. coli
    CMRF35-like molecule 1 (CLM-1) Protein serves as an inhibitory receptor for myeloid and mast cells, crucial in immune homeostasis by regulating various immune responses. CLM-1 positively modulates macrophage-mediated efferocytosis by recognizing phosphatidylserine on apoptotic cells. It inhibits dendritic cell-mediated efferocytosis and Fc epsilon receptor-dependent mast cell activation. CLM-1 may act as a coreceptor for IL-4, enhancing IL-4- and IL-13-induced signaling. Additionally, it negatively regulates TLR signaling and inhibits osteoclast formation while inducing macrophage cell death. The protein interacts with PTPN6/SHP-1 and associates with IL4R. CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO) is the recombinant rat-derived CMRF35-like molecule 1 protein, expressed by E. coli, with N-His, C-Myc, N-SUMO labeled tag. The total length of CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO) is 163 a.a., with molecular weight of ~38.3 kDa.

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