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Results for "

DCLK1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135985
    DCLK1-IN-1
    1 Publications Verification

    		 Others Cancer
    DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1 + pancreatic ductal adenocarcinoma (PDAC) [1].
    <em>DCLK1</em>-IN-<em>1</em>
  • HY-RS03578
    DCLK1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    DCLK1 Human Pre-designed siRNA Set A contains three designed siRNAs for DCLK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DCLK1 Human Pre-designed siRNA Set A
    DCLK1 Human Pre-designed siRNA Set A
  • HY-163184
    DCLK1-IN-3

    		Ser/Thr Protease Cancer
    DCLK1-IN-3 is a potent and selective doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 47 nM. DCLK1-IN-3 can be used for the research of cancer [1].
    <em>DCLK1</em>-IN-3
  • HY-163185
    DCLK1-IN-4

    		Ser/Thr Protease Cancer
    DCLK1-IN-4 (compound D2) is a potent and selective doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 70 nM. DCLK1-IN-4 can be used for the research of cancer [1].
    <em>DCLK1</em>-IN-4
  • HY-155303
    DCLK1-IN-2

    		Ser/Thr Protease Cancer
    DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3  nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency [1].
    <em>DCLK1</em>-IN-2
  • HY-161471
    DCLK1-IN-5

    		Ser/Thr Protease Inflammation/Immunology
    DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis [1].
    <em>DCLK1</em>-IN-5

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