DCLK1 Protein, Human (Active, sf9)
The DCLK1 protein is a possible kinase that may play a role in calcium signaling pathways that regulate neuronal migration during brain development. Its association suggests a key role in coordinating processes critical to normal brain formation. DCLK1 Protein, Human (sf9) is the recombinant human-derived DCLK1 protein, expressed by Sf9 insect cells , with tag free.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
The DCLK1 protein is a possible kinase that may play a role in calcium signaling pathways that regulate neuronal migration during brain development. Its association suggests a key role in coordinating processes critical to normal brain formation. DCLK1 Protein, Human (sf9) is the recombinant human-derived DCLK1 protein, expressed by Sf9 insect cells , with tag free.
The DCLK1 protein emerges as a probable kinase with potential involvement in a calcium-signaling pathway that regulates neuronal migration during brain development. Beyond its developmental role, DCLK1 may also contribute to functions within the mature nervous system. The kinase's association with a calcium-signaling pathway suggests a critical role in orchestrating the intricate processes of neuronal migration, crucial for the proper formation of the developing brain. Furthermore, the implication of DCLK1 in mature nervous system functions hints at its versatility and significance throughout various stages of neural development and function. Further exploration is warranted to elucidate the specific mechanisms and pathways through which DCLK1 exerts its regulatory influence in both developing and mature neural tissues.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
O15075-1 (M1-V705)
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Molecular Construction
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N-term
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DCLK1 (M1-V705)
Accession # O15075 -
C-term
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Protein Length
Partial
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Synonyms
DCLK1; Doublecortin-Like And CAM Kinase-Like 1; Prev. DCAMKL1; Doublecortin-Like Kinase 1; DCDC3A; Doublecortin And CaM Kinase-Like 1; KIAA0369; CLICK1; DCLK; CL1; Doublecortin Domain-Containing Protein 3A; Doublecortin Like Kinase 1; Serine/Threonine-Pro
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AA Sequence
MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDV
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Predicted Molecular Mass
78.5 kDa
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Molecular Weight
Approximately 64 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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