DCLK1 Protein, Human (sf9, His-GST)

The DCLK1 protein is a possible kinase that may play a role in calcium signaling pathways that regulate neuronal migration during brain development. Its association suggests a key role in coordinating processes critical to normal brain formation. DCLK1 Protein, Human (sf9, His-GST) is the recombinant human-derived DCLK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of DCLK1 Protein, Human (sf9, His-GST) is 705 a.a., with molecular weight of ~105 kDa.

The DCLK1 protein emerges as a probable kinase with potential involvement in a calcium-signaling pathway that regulates neuronal migration during brain development. Beyond its developmental role, DCLK1 may also contribute to functions within the mature nervous system. The kinase's association with a calcium-signaling pathway suggests a critical role in orchestrating the intricate processes of neuronal migration, crucial for the proper formation of the developing brain. Furthermore, the implication of DCLK1 in mature nervous system functions hints at its versatility and significance throughout various stages of neural development and function. Further exploration is warranted to elucidate the specific mechanisms and pathways through which DCLK1 exerts its regulatory influence in both developing and mature neural tissues.

Human

Sf9 insect cells

N-His;N-GST

O15075 (M1-V705)

9201  [NCBI]

Approximately 105 kDa

Greater than 84% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.