DCLK1-IN-5
DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis.
For research use only. We do not sell to patients.
- CAS No.: 3028774-14-0
- Formula: C26H32ClN7O3S2
- Molecular Weight:590.16
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 3028774-14-0
-
Molecular Weight 590.16
-
Formula C26H32ClN7O3S2
-
SMILES
O=S(C1=C(NC2=NC(NC3=C(OC)C=C(NC(N4CCN(C)CC4)=S)C=C3)=NC=C2Cl)C=CC=C1)(C(C)C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)