3028774-14-0

DCLK1-IN-5 Chemical Structure
3028774-14-0

Chemical Structure

DCLK1-IN-5

  • CAS No.: 3028774-14-0
  • Formula:C26H32ClN7O3S2
  • Molecular Weight:590.16

InChIKey: AJSKSKGAQOFYCO-UHFFFAOYSA-N

SMILES: O=S(C1=C(NC2=NC(NC3=C(OC)C=C(NC(N4CCN(C)CC4)=S)C=C3)=NC=C2Cl)C=CC=C1)(C(C)C)=O

Biological Activity: DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis[1].

Cat. No. Product Name Purity Description Pricing
HY-161471 		DCLK1-IN-5 DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis.
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