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Results for "

DKK3

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

1

Inhibitory Antibodies

4

Recombinant Proteins

1

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P7812
    DKK-3 Protein, Human (HEK293, His)

    rHuDickkopf-related protein 3/DKK-3, His; Dickkopf-Related Protein 3; Dickkopf-3; DKK-3; hDKK-3; DKK3; REIC

    		 Human HEK293
    DKK-3 protein antagonizes canonical Wnt signaling by blocking LRP5/6-Wnt interactions and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization. In vertebrate development, DKK-3, together with other DKKs, critically inhibits Wnt-regulated processes such as axial patterning, limb development, somitogenesis, and eye formation. DKK-3 Protein, Human (HEK293, His) is the recombinant human-derived DKK-3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DKK-3 Protein, Human (HEK293, His) is 329 a.a., with molecular weight of ~66-73 kDa.
  • HY-P78681
    DKK-3 Protein, Human (R335G, HEK293, His)

    DKK3; REIC; RIG

    		 Human HEK293
    DKK-3 protein antagonizes canonical Wnt signaling by blocking LRP5/6-Wnt interaction and forming a ternary complex with KREMEN, promoting LRP5/6 internalization. In vertebrate development, DKK-3, along with other DKKs, crucially inhibits Wnt-regulated processes like axial patterning, limb development, somitogenesis, and eye formation. In adults, DKKs, including DKK-3, are implicated in diverse conditions like bone formation, bone disease, cancer, and Alzheimer's. DKK-3's interaction with LRP5 and LRP6 underscores its regulatory role in inhibiting Wnt signaling and its potential impact on various cellular processes. DKK-3 Protein, Human (R335G, HEK293, His) is the recombinant human-derived DKK-3 protein, expressed by HEK293 , with C-6*His labeled tag and R335G mutation. The total length of DKK-3 Protein, Human (R335G, HEK293, His) is 329 a.a., with molecular weight of 50-66 kDa.
  • HY-P75287
    DKK-3 Protein, Mouse (HEK293, His)

    Dickkopf-related protein 3; Dickkopf-3; DKK-3; mDKK-3

    		 Mouse HEK293
    The DKK-3 protein antagonizes canonical Wnt signaling by inhibiting LRP5/6-Wnt interaction. It forms a ternary complex with KREMEN, facilitating LRP5/6 internalization. DKK-3, along with other DKKs, plays a critical role in vertebrate development, regulating processes like axial patterning, limb development, somitogenesis, and eye formation. In adults, DKK-3 is implicated in bone formation, bone diseases, cancer, and Alzheimer's disease. DKK-3 also interacts with LRP5 and LRP6, but lacks carboxypeptidase or dipeptidyl-peptidase IV activity. DKK-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DKK-3 protein, expressed by HEK293, with C-His labeled tag. The total length of DKK-3 Protein, Mouse (HEK293, His) is 349 a.a., with molecular weight of ~65 kDa.
  • HY-P77640
    DKK-3 Protein, Human (Biotinylated, HEK293, His-Avi)

    Dickkopf-3; DKK3; REIC; REICDKK-3; RIG; RIG-like 5-6; RIG-like 7-1; AW061014; C87148

    		 Human HEK293
    DKK-3 protein antagonizes canonical Wnt signaling by blocking LRP5/6-Wnt interactions and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization. In vertebrate development, DKK-3, together with other DKKs, critically inhibits Wnt-regulated processes such as axial patterning, limb development, somitogenesis, and eye formation. DKK-3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived DKK-3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of DKK-3 Protein, Human (Biotinylated, HEK293, His-Avi) is 328 a.a., with molecular weight of 50-70 kDa.

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